Bone marrow transplantation is a therapeutic intervention for leukemia, lymphoma but also for a range of non-malignant diseases varying from bone marrow failure syndromes, to immunodeficiency and lysosomal storage disease. At the transplant center of the UMC Utrecht and the Princess Maxima Center for pediatric oncology we transplant these subgroups of patients. As a pediatric immunologist and clinician scientist I am particularly interested to improve their outcomes post transplantation by aiming for strategies to improve immune reconstitution post transplantation and diminish the risk of graft versus host from donor T cells. My lab has a particular focus on tissue damage in the transplant setting and on the development of graft versus host disease. We use the 3D intestinal organoid model to study intestinal damage and recovery in the transplant setting.
This webpage is not affiliated with the UMC Utrecht
